Most Common Side Effect is (See Full list below) Nausea (Recommendations to limit Nausea: Eat bland, low-fat foods, like crackers, toast and rice. Eat foods that contain water, like soup and gelatin. Avoid laying down after eating. Eat slowly. Go outdoors for fresh air.)

IMPORTANT!

THIS PRODUCT FOLLOWS A TITRATION SCHEDULE. ALL PATIENTS MUST START WITH ‘MONTH 1’ DOSE. AFTER MONTH 1, THE DOSAGE PER INJECTION INCREASES GRADUALLY IN MONTH 2, 3, AND 4. LASTLY THE MAINTENAINCE DOSE CAN BE ONGOING FOR UP TO 8 MONTHS DEPENDING ON YOUR GOALS

A MINIMUM BMI OF 27 OR GREATER IS REQUIRED TO ORDER THIS PRODUCT

Shipping

This product can be shipped 2-Day or Overnight and does not need to be refrigerated during shipping. As a precaution, please refrigerate once received and opened.

What is Semaglutide?

Semaglutide an incretin mimetic; specifically, semaglutide is a GLP-1 receptor agonist with 94% sequence homology to human GLP-1. Semaglutide binds and activates the GLP-1 receptor. GLP-1 is an important, gut-derived, glucose homeostasis regulator that is released after the oral ingestion of carbohydrates or fats. In patients with Type 2 diabetes, GLP-1 concentrations are decreased in response to an oral glucose load. GLP-1 enhances insulin secretion; it increases glucose-dependent insulin synthesis and in vivo secretion of insulin from pancreatic beta cells in the presence of elevated glucose. In addition to increases in insulin secretion and synthesis, GLP-1 suppresses Glc secretion, slows gastric emptying, reduces food intake, and promotes beta-cell proliferation. The principal mechanism of protraction resulting in the long half-life of semaglutide is albumin binding, which results in decreased renal clearance and protection from metabolic degradation; semaglutide is stabilized against degradation by the DPP-4 enzyme. Semaglutide reduces blood glucose through a mechanism where it stimulates insulin secretion and lowers Glc secretion, both in a glucose-dependent manner. Therefore, when blood glucose is high,

insulin secretion is stimulated and Glc secretion is inhibited. The mechanism of blood glucose lowering also involves a minor delay in gastric emptying in the early postprandial phase.

An online consult or a telehealth visit consult first or we can do an in person consult as well with that consult. We can also have the medication delivered to your home after the consult.